Research Assistant Job at Case Western Reserve University, Cleveland, OH 44106

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Job Description

Job Description


POSITION OBJECTIVE

Working under moderate supervision, the Research Assistant 1 will perform research into glycogen storage disorders with the objectives to create and characterize cultured cell models of the disorders, and then test various strategies to correct the genes causing them. The responsibilities of the position are to 1) develop and characterize the cell models, 2) collect and analyze samples generated from the project, and 3) assist in the overall operations of the lab, including monitoring supplies and general lab duties. This position will function under the umbrella of the Research Institute for Children’s Health, the goal of which is to explore therapeutic approaches for rare, genetic diseases. This position is a part-time 20 hours per week.


ESSENTIAL FUNCTIONS

  • Perform PCR and enzyme assay experiments. Must be coordinated and data recorded for statistical analyses. (25%)
  • Perform laboratory procedures, including eukaryotic cell culture, molecular biology and biochemistry. This will include mutagenesis and maintenance of cell lines, PCR to assess mutagenesis and gene expression, and assays to assess enzyme activities. (40%)
  • Conduct analysis of samples. The data generated from the experiments must be analyzed, including both summary statistics as well as comparisons of sample means and variation. (10%)
  • Maintain laboratory records. This includes not only experimental data records, but also cataloging cell lines and other samples (DNA, RNA, protein) generated from experiments. (10%)
  • Maintain laboratory instrumentation utilized in experiments. Thermalcyclers for PCR, cell culture facilities and plate readers must all be maintained. (6%)
  • Order laboratory supplies. Reagents for PCR and cell culture, as well as disposables for experiments must remain stocked. (6%)


NONESSENTIAL FUNCTIONS

Perform other duties as assigned; May include shipping samples to collaborators and assisting other lab members when needed. (3%)


CONTACTS

Department: Daily contact with the supervisor and a research associate who will serve as the project director to discuss research and obstacles encountered. The project will also utilize the Small Molecule and Drug Screening Core and thus interact with Core personnel.

University: Little to no contact anticipated, but there may be occasions where materials or information could be exchanged between labs.

External: Occasional contact with collaborators to exchange research material or data.

Students: Regular contact with 1 to 2 students for training and oversight responsibilities during undergraduate summer internship program in the principal investigator’s laboratory.


SUPERVISORY RESPONSIBILITY

This position has no direct supervision of staff.


QUALIFICATIONS

Education/Experience: Bachelor’s degree in science and 0 to 1 year of experience or Associate's degree in an approved biotechnology program and 0 to 2 years of laboratory experience.


REQUIRED SKILLS

  • Has knowledge of commonly-used concepts, practices, and procedures.
  • Relies on instructions and pre-established guidelines to perform the functions of the job.
  • Ability to operate laboratory equipment and instrumentation.
  • Ability to meet consistent attendance and work in a team environment.
  • Ability to interact with colleagues, supervisors and collaborators face to face.


WORKING CONDITIONS

General molecular biology laboratory environment. May have exposure to chemical hazards, such as acids, bases. Personal protective equipment, including lab coat, gloves and goggles, will be provided to limit exposure to hazards. No physical exertion required. No travel required, but attendance at scientific meetings will be offered for presenting research results.


Term Position


This is a Term position. They are treated like regular staff positions for medical and dental benefits eligibility, vacation, holidays, and sick time. Term employees are not eligible for life insurance, retirement, long term disability, short term disability, tuition assistance, layoff status, or severance pay. Staff in term positions are also subject to the performance management review process and positive corrective action when work performance or behavior is unsatisfactory or unacceptable. Term employment does not alter the employment-at-will employee status of these employees.

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Diversity Statement


In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

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Reasonable Accommodations


Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

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COVID Vaccination


Case Western Reserve University has implemented a COVID Vaccination policy requiring evidence of COVID-19 vaccination for all students, faculty and staff with an on-campus presence. Religious and medical exemptions may be provided in accordance with applicable federal and state laws. For more information go to: https://case.edu/equity/covid-19-accommodations. Applicants may contact the Office of Equity at 216-368-3066 /equity@case.edu for information regarding religious or medical exemptions as an accommodation.

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