Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission - to enable our customers to make the world healthier, safer, and cleaner.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

Essential Functions:

The target client is a leading pharmaceutical group responsible for the development of CHO based production cell lines, next-gen cell line engineering efforts and baseline upstream process development for innovative recombinant protein/adjuvanted vaccine projects and platforms. The target client is looking for a motivated professional, specialized in commercial cell line development, CHO protein vaccines. This role will play a significant role in shaping current and next generation leading vaccine platforms to accelerate addressing unmet medical needs, an exciting field having a direct impact into patients and global health. This role provides the opportunity to integrate a diverse group of top talented experts in vaccines’ industry, lead key activities and further grow and progress in your career.

Main core responsibilities:
A. Design and Development of preGMP-grade CHO cell lines for commercial manufacture of recombinant protein vaccine products.

B. Serve as a key team player to support project documentation and CMC regulatory submissions (including raw material control section and cell line derivation report)

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Qualifications - External

Education and Experience:

Bachelor's degree in a degree related in Biochemistry, Molecular Biology, Chemical Engineering, Biotechnology, Bioengineering, or a related scientific field.

• Previous industry experience that provides the knowledge, skills, and abilities to perform the job:
  • Associate Research Scientist: With a bachelor’s degree comparable to 6+ years, with a master’s degree comparable to 4+ years, with a PhD comparable to 2+ years.

Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 6+ years).

Hands-on experience with aseptic mammalian (CHO cell preferred) cell line development, especially transfection, single cell isolation, derivation, suspension cell culture at small scales ranging including 96 well-plate, 24 well-plate and shake flask formats.

Experience with expression vector design and optimization for complex recombinant protein production.

Experience with good documentation practices and reports as evidenced by conference proceeding, peer-review publication and/or equivalent.

Preferred Qualifications:

• Working knowledge in the cell line development for vaccine and biologicals production in the industrial setting (including a strong CMC understanding)
• Prior experience in the high-throughput, robotic cell line screening tools (including FACS and Beacon et al) or other high-throughput robotic systems
• Experience with common nucleic acid- and protein-based analytic assays (including PCR, Luminex and Octet) for early product quantity and quality assessment to support cell line selection. .

Working Environment:

PPD values the health and well being of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.